Dot & Key Water Drench Hydrating Hyaluronic Acid Serum Concentrate

Dot & Key hyaluronic acid serum
Dot & Key’s packaging is pastel and pretty!

As usual, my dilemma for finding the perfect moisturizer has not yet solved. So, after using the hyaluronic acid serum (Marine Hyaluronics) from The Ordinary, this is my second hyaluronic acid serum and I was and was completely unsure of what to expect. The best part is I am writing the review almost a month after finishing the product so I also have in mind how is my skin doing after I have discontinued the serum.

Dot & Key is a recent addition to my knowledge of brands. They have interesting products with their vitamin C and retinol serum still on the review shelf with me. After I finished the hyaluronic acid serum, I started with vitamin C serum and I am almost half way through it. As I have already said, hyaluronic acid is a great hydrating ingredient for the skin and if you have a dry skin, you should give hyaluronic acid serum a try.

Dot & Key Water Drench Hydrating Hyaluronic Serum Concentrate Product Review

Price : Rs 895

Availability : Online Website

Dot & Key hyaluronic acid serum, ingredient list


The packaging mentions key ingredients and not the complete set of ingredient list. The concentration of hyaluronic acid in the serum which proves the efficacy of such treatment serums is also missing. However, I am liking other ingredients in the list though the same argument goes for them too.

concentration of ingredients is unknown because of the lack of complete
ingredient list. Bulgarian rose oil and acai berry fruit oil look really
interesting. Milk lipids help moisturize the skin. Ceramide 3 gets absorbed
into the skin and improves the skin barrier, thus, helping the appearance of
aging skin.

My Review

When used topically, hyaluronic acid creates a moisture barrier on the skin, helping to make it smoother and softer. This ingredient is able to hold up to 1000x its own weight in water, thus producing amazing benefits for dehydrated skin. (Source –

Dot & Key hyaluronic acid serum

The serum comes in a nice blue robust bottle with a stopper. The serum is transparent and runny in texture. It has a mild fragrance to it which I did not like the first time.  But the smell did not interfere with my nose at all and dissipates as soon as I apply the serum on the face. Since the texture is runny, you have to be careful about applying it.

I started using the serum in mid-July and it lasted me almost a month with a complete pump for one time use twice a day. Since this is only a hyaluronic acid serum, it is not enough for complete moisturization so I paired it up with Organic Riot Dazzle serum. It is advisable to follow up with a moisturizer for any kind of serum or treatment you use.

As I mentioned earlier, the hyaluronic acid serum is very runny so I apply it in dots all over the face and neck and gently rub it in. The serum gets absorbed pretty quickly and does not leave any sticky feeling behind. In fact, it is easy to say skin drinks up the serum instead. However, the serum alone is not enough for me and I need to follow it up with moisturizer for sure otherwise my skin feels stretchy.    

Dot & Key hyaluronic acid serum, vitamin C serum, retinol serum
Love their packaging!

The serum does make the skin glow and hydrates it from inside though on some days it might not be enough depending on how you take care of your skin and the weather outside. The hydration lasts for an entire day even if you do not wash our face at night. It keeps the skin hydrated in air-conditioned environment as well for the entire day with a moisturizer. After I finished with the hyaluronic acid serum, I could actually feel my skin getting drier.

Overall, I loved the product especially considering that it is Rs 900. There are very few hyaluronic acid serums at that price range in the market and this is one of them which does a pretty good job. So, yes, you should make hyaluronic acid serum a part of your daily skin care routine. I also have Dot & Key’s vitamin C and retinol serum up for review in the upcoming weeks so stay tuned for them!

I would like to apologize to the brand as well. This review has been delayed for too long as I could not really find time to click pictures and put them up for the review. To update you about changes in my life, I recently started working again full time and since then my routine has been all over the place which is why the posts are sporadic. I am still trying to get everything back under control.

Till then, Swathy.

The post Dot & Key Water Drench Hydrating Hyaluronic Acid Serum Concentrate appeared first on Perfect Skin Care for you.

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2020: A New Decade for Hepatitis C Drugs and Eradication

2019 was a big year in the fight against the hepatitis C virus (HCV). It introduced several new therapies as well as discontinued a handful of others. There was also no shortage of research and review pouring into the HCV space with newly improved therapies and practices being constantly explored. Out with the old and in with the new – most notably:

  • generic antiviral treatments
  • cost-friendly treatment options
  • and better treatment options for children with HCV.

The Politics

One of the largest political changes in the HCV fight has become the overwhelming unity of local state bodies and their willingness to set agendas that address HCV and take actionable steps towards eradication. Louisiana set a 2024 date on the eradication of hepatitis C recognizing it as a public health concern (1). Their plan of attack is comprised of “seven strategies leveraging mutually reinforcing efforts across public health, health care, industry and community partners throughout the state working towards the common goal of diagnosing 90% and treating 80% of Louisiana residents living with hepatitis C (1).” You can read the entirety of Louisiana’s plan HERE.

Other states like Georgia have also followed suit creating state-wide guidelines, budgets and timelines largely aimed at spreading hep c awareness that can link to diagnosis to treatment and care (2).

However, looming in the background are The World Health Organization’s 2030 elimination targets (3), and some critics believe we may be off track as screening and prevention lags in the U.S. (4). That’s why it’s possible that amidst all the focus and resources directed at the hepatitis C issue, the national rates of hepatocellular carcinoma and chronic liver diseases are on the rise while national rates of other cancers have been declining and stabilizing for the past 25 years (5).

The Last Hurdle: Awareness

One key to curbing hepatocellular carcinoma rates will be our ability to identify who HCV patients are, as oftentimes symptoms are hard to identify and can go unnoticed for years. Awareness in 2020 and information about hepatitis C is the only thing that will turn the tide.

The Best Treatment for Hep C: DAAs

Since their FDA approval in 2014, direct-acting antivirals (DAAs) have been regarded as the most effective treatment option for hepatitis C patients with impressive cure rates, and 2020 is looking like no exception (6).

Currently, the most recently approved DAAs are Mavyret and Vosevi, both of which came to market in 2017 (6). Wholesale Mavyret will run you roughly $24,000 while Vosevi can be up to $74,000 for a 12-week treatment period. And, in those numbers, the issues of cost and access begin to reveal themselves.

As DAAs continue to evolve, they’re being designed to have fewer side effects and quicker treatment durations. One such phase 2 clinical trial with published findings in Hepatology, found 6-8 week reduced treatment periods to be highly effective for several FDA approved DAAs including odalasvir and simeprevir (7).

2019 DAA Discontinuations

DAAs discontinued in the last year were Technivie (ombitasvir/paritaprevir/ritonavir) and Viekira Pak (ombitasvir/paritaprevir/ritonavir plus dasabuvir). And all Daklinza tablets have been discontinued as of June 2019 (6).

The current duration of most standard DAA treatments sits between 8-12 weeks, which may seem like a short period of time for an adult, but that same timeframe can greatly impact more vulnerable groups of the population, specifically children. That’s why 2019 witnessed big progress for DAAs directed towards children with HCV. 2019 saw the introduction of many highly effective “short-course oral pan-genotypic DAA regimens” specifically for young kids (3). Harvoni is one such DAA that recently proved safe and effective for children in the 3-6 year range in a study published by the American Journal of Clinical Health (8).

But even as wider ranges of the population gain access to highly effective DAAs, it’s important to anticipate and understand some of the most common side effects:

  • Fatigue
  • Headaches
  • Nausea
  • Weakness
  • Insomnia
  • Diarrhea

Knowing what to expect as a caregiver or patient heading into DAA treatment is critical. Knowledge is power, and a sense of control surrounding treatment can be extremely helpful for the mindset of anyone going through treatment.

How Much Does Hep C Treatment Cost?

While the cost of DAAs has been declining beginning with the release of Mavyret in 2017 at the low cost of $26,400 per round of treatment, for the average HCV sufferer treatment can represent an extreme burden. As the price wars continued, Gilead authorized a generic version of Harvoni and Epclusa. Generic Harvoni and Epclusa costs approximately $24,000, a significant difference when you consider brand name Harvoni can cost roughly $94,000 and Epclusa can cost about $74,000 for a standard 12-week treatment (10).

While hepatitis C treatment success rates are at an all time high (close to 95% for most cases!), as far as leading researchers and science is concerned in deciding the best treatment for hepatitis C, a combination of primary and secondary care is increasingly becoming the norm due to dramatically increased outcomes (11). This means coordination between primary care physicians and the HCV specialist who can keep patients up-to-date on the leading DAAs and treatment options. While it may seem like common sense, sometimes it’s not an option due to financial limitations, but primary and secondary care combinations lead to more comprehensive and transparent care.

Next Step: Screening & Prevention

With full awareness that we are in the era of the DAA, most hepatitis C patients, if diagnosed, stand a high chance of being cured. But what does that mean for the majority of the suspected undiagnosed HCV cases worldwide (3)? In a European modeling study published in the BMJ, researchers found “scaling-up screening and treatment capacity, and timely and effective retreatment are needed to avail the full benefits of DAAs and to meet HCV elimination targets set by WHO (12).” So, ultimately, the burden will fall on comprehensive screening programs and prevention.

While the 2010s will be marked as the decade we realized how bad the problem was, hopefully the 2020s will be the decade we get a grip on hepatitis C prevention and awareness. And in doing our small part through spreading awareness and information, hopefully we can all make WHO’s 2030 elimination date a reality.

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6 Benefits of Homemade Meals

Nо one can deny thаt going оut to еаt аnd having someone еlѕе рrераrе уоur mеаlѕ іѕ a grеаt соnvеnіеnсе. But, cooking уоur оwn food аt hоmе hаѕ a number оf bеnеfіtѕ аѕ well.

It’s muсh easier аnd quicker tо еаt оut оr get a tаkеаwау, оr еvеn to оrdеr one frоm hоmе thаn tо stand аnd cook уоur оwn ѕuрреr. But іѕ іt bеttеr? No, we аll knоw іt’ѕ not. It’ѕ commonly knоwn thаt tоо much fast-food еаѕіlу lеаdѕ tо оvеrwеіght, аnd it hаѕ bееn рrоvеn thаt rеаdу-mаdе mеаlѕ and рrосеѕѕеd foods саn have quite a negative іmрасt оn уоur health. Bеѕіdеѕ thаt, it’s еxреnѕіvе tо live lіkе that. Let me gіvе уоu six vаlіd rеаѕоnѕ whу іt’ѕ wоrth tо prepare уоur оwn meals. Your fаmіlу wіll сеrtаіnlу bеnеfіt frоm home-made meals, as thеу mean.

Here are the 6 benefits of homemade meals:

  • More quality time tоgеthеr

Cооkіng саn be a jоіnt аdvеnturе. If уоu have еvеr сооkеd wіth a friend, you wіll knоw hоw much fun іt can be. This іѕ аn еxсеllеnt орроrtunіtу to ѕреnd tіmе wіth уоur lоvеd ones. Eѕресіаllу іnvоlvіng уоur kіdѕ саn be a great іdеа, as they саn lеаrn a lоt whilst сооkіng wіth уоu.

  • Imрlеmеntіng hеаlthу eating hаbіtѕ

Cооkіng together іѕ аn excellent lеѕѕоn for уоur children. Tеасh thеm tо make hеаlthу fооd choices, аnd hоw tо рrераrе fооd іn a hеаlthу wау. If thеу ѕtаrt еаrlу and еnjоу сооkіng with уоu, thеу аrе likely tо сооk fоr thеmѕеlvеѕ lаtеr оn, аnd уоu саn еnѕurе thеу knоw how tо dо іt рrореrlу. Yоu gіvе thеm a great ѕtаrt fоr lіvіng a hеаlthу lіfе whеn they are grоwn uр, аnd they аnd their fаmіlіеѕ wіll оnlу bеnеfіt frоm thаt. If you dоn’t teach your сhіldrеn, who wіll?

  • Getting уоur kіdѕ to eat hеаlthу fооdѕ

This is аn old but vеrу еffесtіvе trісk to get сhіldrеn tо еаt these hеаlthу fооdѕ. Chіldrеn are uѕuаllу mоrе рrераrеd tо eat a mеаl whеn thеу hеlреd in to рrераrе іt. If you ѕhоw you appreciate thеіr hеlр аnd lеt thеm fееl thеу dіd a grеаt jоb, this саn аlѕо bооѕt thеіr ѕеlf-еѕtееm.

  • Appropriate роrtіоnѕ

Restaurants are notorious for thеіr extreme роrtіоn sizes, which mау соntrіbutе to thе vаѕt overeating сulturе аnd оbеѕіtу іѕѕuе in Amеrіса. Preparing mеаlѕ аt hоmе gіvеѕ уоu thе ability tо еxеrсіѕе роrtіоn соntrоl and hеlр сurb thе tеmрtаtіоn оf overeating.

  • Inсrеаѕіng your family’s hеаlth

Hеаlthу eating is аn іmроrtаnt key to bеіng hеаlthу. By рrераrіng уоur оwn meals, you hаvе tоtаl control over whаt gоеѕ іntо them, аnd you саn ensure your family gets the hеаlthіеѕt fооd уоu саn fіnd. If уоu fееd them hеаlthу, thеу are unlіkеlу tо dеvеlор weight problems, аnd уоu саn ѕіgnіfісаntlу reduce their risk to ѕuffеr іllnеѕѕеѕ like diabetes, саnсеr, hеаrt аttасk оr stroke.

  • Saves mоnеу

If you eat оut often оr buy lots оf tаkеаwауѕ, уоu knоw hоw much of a strain this рlасеѕ оn уоur budget. If уоu buу уоur own groceries аnd рrераrе the mеаlѕ уоurѕеlf, уоu will ѕреnd muсh lеѕѕ mоnеу on fооd, mеаnіng уоu wіll hаvе mоrе mоnеу fоr оthеr treats, lіkе tаkіng thе kіdѕ to the movies or gоіng away for a weekend wіth your partner. Fооd is аn еxсеllеnt ѕоurсе оf ѕаvіng mоnеу: Simply cut dоwn оn these “аddіng” lіkе cream оr ѕаuсеѕ whісh аrе оftеn hіgh in саlоrіеѕ, buу lаrgе росkеtѕ of vеgеtаblеѕ at a special store іnѕtеаd of tins, and сhесk whісh fооdѕ аrе іn ѕеаѕоn and therefore сhеар rіght now. Yоu ѕhоuld, thоugh, ensure thаt уоur dіеt is balanced.

As уоu can see, cooking іѕ аbоut mоrе than just рrераrіng a mеаl. It саn bе a ѕосіаl event, ѕрісіng uр уоur family life аnd bringing уоu closer. It can bе fun аnd еduсаtіvе at thе ѕаmе time. It can mаkе a grеаt роѕіtіvе impact on уоur hеаlth, and it saves you mоnеу. What mоrе соuld you wаnt? Trу it оut аnd ѕее hоw іt will wоrk fоr уоu!

The post 6 Benefits of Homemade Meals appeared first on Raising a Healthy Family.

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How to Break the Coronavirus Anxiety Cycle

From the psychiatrist Judson A. Brewer, M.D., Ph.D. in the NYTimes:

Anxiety and its close cousin, panic, are both born from fear and uncertainty. We have plenty of that with the current COVID-19 pandemic.

If information is lacking, our prefrontal cortex lays out different scenarios about what might happen. Some of these scenarios can be pretty scary.

Anxiety is contagious. The spread of emotion from one person to another is called social contagion. “People can sneeze on your brain”, says Dr Jud. “Our own anxiety can be cued or triggered simply by talking to someone else who is anxious. Their fearful words are like a sneeze landing directly on our brain, emotionally infecting our prefrontal cortex, and sending it out of control as it worries about everything from whether our family members will get sick to how our jobs will be affected.”

To break the anxiety cycle, do 2 things:

1. become aware when you are getting anxious or panicking and what the result is.
2. bring in the “bigger better offer” (BBO).

What is the “bigger better offer” (BBO)? Your brain will choose more rewarding behaviors simply because they feel better. Replace old habitual behaviors — such as worry — with those that are naturally more rewarding.

An example: If you notice that your touched your face, and start to worry: “Oh no, I touched my face, maybe I’ll get sick!”, instead of panicking, take a deep breath and ask: “When was the last time I cleaned my hands?”. Think. “Oh, right! I just washed my hands.” Here, we can leverage certainty: If we’ve just washed our hands, and haven’t been out in public, the likelihood that we’re going to get sick is pretty low.”

Dr Jud: “Understanding these simple learning mechanisms will help all of us “keep calm and carry on” (which is how London dealt with the uncertainty of constant air raids in World War II) instead of getting caught in anxiety or panic in the coming days, and whenever we face uncertainty.”

You will understand this more clearly if you watch some of Dr Jud’s videos below. He has a coronavirus playlist:

There is also a longer explanation here: The 3 WAYS To Keep Coronavirus ANXIETY From Going VIRAL | Judson Brewer & Lewis Howes:


A Brain Hack to Break the Coronavirus Anxiety Cycle

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Interdisciplinary rounds: A must for hospitals committed to quality

by Raymond Hino

Throughout my career in hospitals and healthcare, I have always been drawn to the ritual of daily patient rounds. I have had the privilege of working in hospitals as large as a 430-bed urban teaching hospital and as small as 25-bed rural community hospitals. Every hospital experience has been unique and highly rewarding in its own way, but one common denominator for me is that the best hospitals that I have worked in have often made good use of daily interdisciplinary rounds.

For example, the teaching hospitals are renowned for the phenomena of daily teaching rounds in which the teaching staff lead a troop of young interns and residents. But I have been equally impressed when I worked in a small hospital in rural Montana and our four-member medical staff made a practice of conducting morning rounds together, along with the nursing staff to get the maximum medical care for each of our hospital’s inpatients. How great it was for each of our patients to receive decades of medical and nursing experience.

I am proud to say that my current hospital, a community hospital in Northern California, has found a valuable role for daily interdisciplinary rounds. Our rounds are attended by hospitalists, social workers, rehabilitation professionals, nurses, pharmacists, infection prevention specialists, dietary experts, case managers and discharge planners. Sometimes even an occasional hospital CEO will stop by to observe the process. All are welcome and encouraged to contribute.


Recently, one of our new nurses said, “This is so great! I have only read about interdisciplinary rounds, but never experienced them before.”

Rounds usually begin, promptly at 11 a.m. with an overhead page to alert our team that it is “time for rounds.” Our team assembles in a conference room, located close to the patient rooms for convenience of our staff. Each patient is presented by their nurse, with any updates and valuable insights into the care plan for the day. This is a wonderful opportunity for clinical staff to interact, communicate and plan for the best outcomes.

Interdisciplinary rounds are a significant time commitment and financial investment by our facility. However, they are well worth the cost. Can you imagine the combined salaries for everyone in the room? The advantage is that we are able to use our work time to address the most important aspects of care and to identify priorities. We have also found that by doing rounds, we are providing individualized care to meet our patients’ immediate needs.

Some positive benefits include opportunities to clarify drug orders, and sometimes to change the orders based upon input from the pharmacists. Most importantly, we have found that our patients become more personal to our staff. Dietary concerns are addressed from intake to NPO for procedures, as are the need for patient and family education or food preferences. Social services and counseling needs are addressed, which is especially important for difficult cases. And there is no doubt that patient safety is enhanced through the experience and medical errors are reduced.

We highly recommend interdisciplinary rounds to all other hospitals. The quality of our communications have been greatly enhanced with our patients and their care teams, including family, primary care providers and caregivers. It is clearly a win-win situation.

Raymond Hino, MPA, FACHE, is the president and CEO of the Sonoma West Medical Center in California.

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Antidepressant may improve cognitive symptoms in people with HIV

In a small, placebo-controlled clinical trial, Johns Hopkins physicians report that the antidepressant paroxetine modestly improves decision-making and reaction time, and suppresses inflammation in people with HIV-associated cognitive impairment. The researchers say they believe this is the first time that a SSRI (selective serotonin reuptake inhibitor) has been shown to improve key measures of cognition in people with HIV in a controlled study.

The researchers note that many patients with HIV-associated neurocognitive disorders may already be benefiting cognitively by taking SSRIs in the dosages used in their study to treat depression, but the new study lends more rigorous scientific support to the drug’s value.

The Johns Hopkins researchers are expected to present their findings Feb. 25 at the Conference on Retroviruses and Opportunistic Infections in Boston.

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Mobilizing medicine: a breathtaking solution to asthma disparities

Asthma is one of the most common chronic diseases in the U.S., with a prevalence of 15.2 percent. The condition is manageable when treatment is appropriately prescribed, adjusted, and accessed by the patient. However, uncontrolled asthma can impair various facets of life and may even be fatal. This dichotomy is noteworthy, especially when considering how […]

Find jobs at Careers by KevinMD.comSearch thousands of physician, PA, NP, and CRNA jobs now. Learn more.

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Indigestion Problems? Try Betel Leaf For Digestion, Constipation And Gastric Pain

Chewing a paan or betel leaf after meal is an ancient food tradition in India. After lunch or dinner, people usually make their way to the tiny paan shops to savour paan, while some make them at home by wrapping gulkand (rose preserve), chopped areca nut, dry roasted fennel seeds, coconut powder, honey, cloves and cardamom pods. But, did you know that this heart-shaped leaf is not only used to make paan?It is also known to have many health benefits and has been extensively used in Ayurveda. Yes, you read that right! According to Ayurveda, chewing paan after meals eases digestion as it increases secretion of digestive juices, reduces bloating of stomach, relieves constipation and destroys intestinal parasites. We tell you some amazing betel leaf benefits.

Betel Leaf For Healthy Digestion

Betel leaf has properties that are carminative, gastro-protective and anti-flatulent, all of which are known to accelerate good digestion. It stimulates the release of saliva, which is the first step of digestion, as various enzymes in it break down food, making it easy to digest. But, if you don’t like its strong mint-like flavour, the best way of reaping its benefits is by creating oil out of betel leaf and massaging it on your stomach, which will help the secretion of gastric juices and digestive acids. However, in the case of kids with digestive problems, the best way to make use of betel leaves is by boiling them with peppermint leaves in water. Strain the water and give it to the younger one daily for effective recovery.

Betel Leaf For Constipation

Betel leaf is packed with vitamin C that helps the body get rid of free radicals. Moreover, the antioxidants help manage the pH level of stomach. All you have to do is to soak the betel leaf in water and store it overnight. Drink the water on an empty stomach next morning or you can just chew the soaked betel leaf.

Betel Leaf Reduce Gastric Pain

Betel leaf normalises the unbalanced pH level of the stomach that gives fast relief from gastric pain, acidity and pain aroused due to bloating problem. Moreover, it also keeps the duodenum clear of dangerous free radicals as well as toxins. This makes it very efficient in improving GERD (Gastroesophageal Reflux Disease).
Back in the days, paan was consumed due to its digestive properties. Those who felt heavy and bloated post any meal and had severe constipation issues, paan used to be a saviour for them. However, it is advised to maintain a gap of at least 30 minutes between consumption of paan and your meal.
Disclaimer: This content including advice provides generic information only. It is in no way a substitute for qualified medical opinion. Always consult a specialist or your own doctor for more information. Healthy Tipping Point does not claim responsibility for this information.

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